Scientist - Biocatalysis & Process Development
Absolute
Gurugram, Haryana, India
Title: Scientist - Biocatalysis & Process Development
Location: Gurugram
About Us
Absolute is a bioscience company founded with the vision of creating a shared future where both people and the planet thrive together. By harnessing the power of nature, science, and exponential innovation, Absolute aims to build a sustainable and prosperous future.
Absolute’s Bio division has evolved into a generation-defining bioscience company operating across Agriculture, Human Health, and Sustainable Materials. With operations in 30+ countries, Absolute’s Agtech businesses span Climate Solutions, Soil Health Testing, Crop Insurance, and Tech-driven Commodities Trade.
Backed by Sequoia, Tiger Global, and Alpha Wave, Absolute’s angel investors include Nadir Godrej (MD, Godrej Industries), Kamal Aggarwal (Promoter, Haldiram), and Kunal Shah (Founder, CRED). The company’s breakthroughs are powered by Xenesis — a team of 150+ scientists driving innovation across disciplines.
Job Description
We are looking for a driven scientist to lead the development of integrated biocatalytic processes for semi-synthetic small-molecule APIs. This role will focus on designing efficient one-pot enzymatic systems and translating lab-scale reactions into scalable, pilot-ready processes.
What You’ll Do
- Design and optimize multi-step enzymatic reaction cascades for API synthesis, including coupling of core scaffolds with functional side-chain donors.
- Develop and evaluate advanced solvent and media systems (e.g., aqueous biphasic systems, ionic liquids) to enhance selectivity, yield, and productivity.
- Implement in situ product removal (ISPR) strategies and enzyme immobilization techniques to improve space-time yield, catalyst stability, and reusability.
- Translate bench-scale reactions into controlled reactor operations (1–5 L scale), supporting process scale-up and robustness.
- Collaborate with cross-functional teams to drive process integration and techno-economic evaluations.
- Generate high-quality experimental data, process documentation, and technical reports.
What We’re Looking For
- PhD in a relevant discipline (Biochemical/Chemical Engineering, Biotechnology, or related) with a minimum of 3+ years of postdoctoral or industry experience; OR MTech/MSc with 7+ years of relevant industry experience in biocatalysis or enzymatic process development.
- Strong track record in enzyme-catalyzed synthesis for APIs, fine chemicals, or related industries
- Expertise in reaction optimization, enzyme stability, and process development
- Experience with immobilized enzymes, heterogeneous biocatalysis, or continuous/packed-bed reactor systems is a strong advantage
- Ability to translate lab-scale processes into scalable manufacturing solutions.
Join Absolute
Be part of a pioneering bioscience company shaping the future of sustainable innovation.